Formation of new base pairs between inosine and 5-methyl-2-thiocytidine derivatives.
نویسندگان
چکیده
In this paper, we report DNA and 2'-OMe-RNA probes containing 5-methyl-2-thiocytidine (m(5)s(2)C) residues that can bind selectively and strongly to the corresponding RNA targets containing inosine residues by the significant stacking effect and steric hindrance of the 2-thiocarbonyl group.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 10 شماره
صفحات -
تاریخ انتشار 2012